|
1
|
|
|
2
|
- EFSA’s mission in relation to Bird Flu
- EFSA’s tasks performed on Bird Flu
- Future EFSA’s tasks on Bird Flu
- Conclusions
- Aknowledgements
|
|
3
|
|
|
4
|
- Provision of scientific advice and scientific & technical support in
all fields which have a direct or indirect impact on Food and Feed
Safety to the EU Commission, MS, EU Parliament (following WTO and SPS
Agreement)
- Provision of independent information on all matters within these fields
- Risk communication
- Networking and collaboration
|
|
5
|
|
|
6
|
- Panel on contaminants in the food chain
- Panel on food additives, flavorings, processing aids and materials in
contact with food
- Panel on dietetic products, nutrition and allergies
- Panel on biological hazards
- Panel on additives and products or substances used in animal feed
- Panel on genetically modified organisms
- Panel on animal health and welfare
- Panel on plant protection products and their residues
- Panel on Plant health
|
|
7
|
- deals with questions on biological hazards relating to food safety and food-borne
diseases including food-borne zoonoses, transmissible spongiform
encephalopathies, food microbiology, food hygiene and associated waste
management
|
|
8
|
- Overlaps : EFSA / EMEA / ECDC/ NON FOOD SCIENTIFIC COMMITTEES
|
|
9
|
- 2. EFSA’s tasks performed on Bird Flu
|
|
10
|
- January. 2004- AHAW -Statement on AI
- September 2005- AHAW Scientific
Report and Opinion on animal
health and welfare aspects of AI
- March 2006 –BIOHAZ -Scientific report on Food as a possible source of
infection with HPAI viruses for humans and other mammals
- May 2006 –AHAW-Report and Opinion on Migratory birds and their possible
role in the spread of highly pathogenic AI-Asian lineage
- November 2006. AHAW- risks
associated with the import of wild bird other than poultry into EU
(exotic/petbirds)
|
|
11
|
|
|
12
|
|
|
13
|
|
|
14
|
|
|
15
|
- EU Policy was in favour of Stamping out:
- not incentives for vaccination and DIVA strategy
- Recent changing Policy:
- in favour of vaccination (even OIE)
- BUT there is a lack of tools
- Vaccinated animals can not be exported according with OIE Rules
- disease notification and vaccination in a country means loss of money
- Pilot projects: still less than 0.1% of the EU poultry are vaccinated
|
|
16
|
|
|
17
|
|
|
18
|
|
|
19
|
- This scientific document analyses whether consuming food contaminated
with HPAI (AI) virus could initiate infection in mammals via the
digestive route.
- Examinig existing data on AI, and H5N1 in particular, studying various
aspects of the virus’s transmission in relation to food and the
gastrointestinal tract.
|
|
20
|
- There is no evidence that the virus replicates in the human intestine.
- Even if virus uptake in the GI tract were possible, e.g. via nerve
endings as was suggested in the experimentally inoculated cats, the
chances that these endings would be hit are very slim.
- Viral RNA or infectious virus may have been produced in throat or
respiratory tissues and swallowed, or could have reached the intestine
after generalisation from other infected targets.
|
|
21
|
- Food that contains virus could be a source of infection if viral uptake
were to occur via oropharingeal tissues. The existence of an undisclosed
target cell in the intestinal tract cannot be ruled out.
- Infection in humans occurs rarely and particularly after very close
contact with infected animals. It is, likely that a high dose of virus
may be needed to initiate an infection and that a readily accessible
entry route for the virus does not exist.
- Experimental studies on the exact route(s) of H5N1 virus entry in
mammals are needed and may provide useful information for the human
infection.
|
|
22
|
|
|
23
|
|
|
24
|
|
|
25
|
|
|
26
|
|
|
27
|
|
|
28
|
- December 2006. AHAW. Revision of the migratory birds opinion in the
light of the last report of DG ENV : species involved and enlarging
recommendations for surveillance.
- January 2007. SCA. Epidemiological Analysis of the current outbreaks in
the EU.
- February 2007 AHAW Vaccination against avian influenza of H5 and H7
subtypes in birds kept in zoos
- April 2007 AHAW. AI Vaccines on
H5-H7 subtypes in domestic birds
- 2007 BIOHAZ continuously evaluating scientific
evidence with respect to AI and food safety
- 2007 AHAW Update of the Risk
assessment of AI in AH -overall assessment on the risk of the entry of
H5N1 to the EU including latest findings and developments
|
|
29
|
|
|
30
|
- Control of outbreaks of Asian lineage H5N1 HPAIv: worldwide top priority
to reduce/avoid risks
- Veterinary structure, control & BIP,
are critical points (awareness, diagnostic and quick
measures)-Increase alert/surveillance systems (e.g. EU)
- Trade live animals & commodities: main concern
- Biosafety measures in all poultry productions systems . Migratory birds
- Info Exchange between Vet-Medical services
- RESEARCH and support to affected countries
|
|
31
|
|
|
32
|
|
|
33
|
|
|
34
|
- Aviflu 2002/6 (final)
- to improve diagnosis and control, it proven that vaccination could be
an effective approach to manage outbreaks;
- Fluaid 2006/8 (cont. Aviflu)
- Studies on vaccine application and DIVA test, to evaluate the consequences of vaccination in
terms of transmission and persistence;
- EPIZONE 2006/11
- Network collaboration, 20
institutions, on epizootic infections, will cover diagnostics, intervention
strategies, surveillance and epidemiology and risk assessment.
|
|
35
|
- AHAW /BIOHAZ Panels -42 members
- Chairmen of the WGs: I. Capua , M. Pensaert, D. Pfeiffer ,
M.Sharp, A. Osterhaus
- Ad hoc Experts giving scientific advice and support : >50 experts
involved
- Commission services: SANCO, ENV, ENT
- FAO, OIE, ECDC , EMEA
- EFSA staff - officials &
administrative support
|
|
36
|
|
|
37
|
|
Notes
